Preheat the air fryer to 400°F (200°C).
In a large mixing bowl, combine the butternut squash cubes, olive oil, salt, pepper, garlic powder, and dried thyme.
Toss the ingredients until the squash cubes are evenly coated with oil and seasonings.
Place the squash in the air fryer basket in a single layer, working in batches if necessary to avoid overcrowding.
Cook for 20 minutes, shaking the basket halfway through the cooking time, until the squash is fork-tender and the edges are browned.
Remove from the air fryer and serve immediately.