Preheat the air fryer to 400°F (200°C) for approximately 3 minutes.
Place the tortilla on a flat work surface and brush the outer 1/2-inch edge with olive oil to facilitate browning.
Apply pizza sauce to the center of the tortilla, spreading it outward while maintaining the 1/2-inch border.
Distribute the shredded mozzarella cheese evenly over the sauce layer.
Arrange pepperoni slices across the cheese and finish with a sprinkle of Italian seasoning.
Carefully transfer the assembled pizza into the preheated air fryer basket.
Cook at 400°F (200°C) for 3 to 5 minutes, or until the cheese is fully melted with golden-brown spots and the edges of the tortilla are rigid and crisp.
Extract the pizza using a flat spatula and allow it to rest for 60 seconds to set the cheese before slicing.