Preheat oven to 350°F (175°C) and grease a 9x5 inch loaf pan.
In a large mixing bowl, sift together the 2 cups flour, sugar, baking powder, and salt.
In a separate bowl, whisk together the melted butter, milk, egg, and vanilla extract until emulsified.
Toss blueberries with 1 tablespoon of flour in a small bowl to prevent fruit precipitation during baking.
Incorporate the wet ingredients into the dry ingredients using a spatula until just combined; do not overwork the gluten.
Gently fold the floured blueberries into the batter.
Transfer the batter into the prepared loaf pan and level the surface with an offset spatula.
Bake for 50 minutes or until an internal temperature of 200°F-205°F is reached or a probe comes out clean.
Allow to cool in the pan for 10 minutes before transferring to a wire rack for final cooling.