Preheat oven to 400°F (200°C) and line a baking sheet with parchment paper.
Quarter the artichoke hearts and ensure they are thoroughly dried with paper towels.
Set up three shallow bowls: one with flour, one with beaten eggs, and one with a mixture of Panko, Parmesan, garlic powder, oregano, salt, and pepper.
Dredge each artichoke quarter in flour, shaking off excess.
Dip the floured artichoke into the egg wash until fully coated.
Press the artichoke into the Panko-Parmesan mixture, ensuring all sides are covered.
Place coated artichokes on the prepared baking sheet in a single layer.
Drizzle with olive oil and bake for 20 minutes, flipping halfway through, until golden brown and crispy.
Serve immediately while hot.