Preheat oven to 400 degrees Fahrenheit and line a baking sheet with parchment paper.
In a medium bowl, mix together the softened light cream cheese, shredded cheddar cheese, garlic powder, and onion powder until well combined.
Fill each jalapeno half with the cheese mixture, leveling the top with a spoon or spatula.
Dip the cheese-filled side of each jalapeno into the crushed tortilla chips, pressing gently to ensure the topping adheres.
Place the stuffed peppers on the prepared baking sheet with the chip-covered side facing up.
Bake for 18 to 20 minutes until the jalapenos are tender and the chip topping is toasted and golden.
Remove from the oven and allow to rest for 5 minutes before serving.