Preheat oven to 400°F (204°C) and line a large baking sheet with parchment paper.
Finely mince the broccoli florets until they reach a rice-like consistency, ensuring any excess moisture is blotted away with a paper towel.
In a large mixing bowl, combine the ground turkey, minced broccoli, shredded cheddar, almond flour, egg, garlic powder, onion powder, salt, and pepper.
Mix the ingredients by hand until just incorporated, being careful not to over-compress the meat.
Portion the mixture into approximately 20 uniform balls, roughly 1 inch in diameter, and place them on the prepared baking sheet.
Bake for 18 to 20 minutes, or until the internal temperature reaches 165°F (74°C) and the exterior is lightly browned.
Remove from the oven and allow the poppers to rest for 3 to 5 minutes to set before serving.