Preheat the oven to 400°F (200°C) and line a rimmed baking sheet with parchment paper.
In a shallow dish, combine the Panko breadcrumbs, grated Parmesan cheese, garlic powder, paprika, salt, and black pepper.
Pat the chicken breasts dry with paper towels to ensure optimal adhesion.
Brush each chicken breast evenly with a thin layer of mayonnaise on all sides.
Dredge the chicken in the breadcrumb mixture, pressing firmly to ensure the crust adheres to the surface.
Arrange the chicken on the prepared baking sheet and drizzle the tops evenly with melted butter.
Bake for 18 to 20 minutes, or until the internal temperature reaches 165°F (74°C) as measured by an instant-read thermometer.
Remove from the oven and allow the chicken to rest for 5 minutes before serving to retain moisture.