Preheat oven to 400 degrees Fahrenheit (204 degrees Celsius).

Line a large rimmed baking sheet with parchment paper or a silicone baking mat.

Arrange the pepperoni slices in a single layer on the prepared baking sheet, ensuring they do not overlap.

Bake for 8 to 10 minutes until the edges are dark and the centers are bubbling.

Remove the baking sheet from the oven and transfer the pepperoni slices immediately to a plate lined with paper towels.

Allow the chips to cool for 2 to 3 minutes to reach maximum crunch.