Preheat the oven to 425°F (220°C).
Wash the asparagus spears and pat them thoroughly dry with a paper towel to ensure roasting rather than steaming.
Place the trimmed asparagus on a large rimmed baking sheet.
Drizzle the olive oil over the spears and sprinkle evenly with kosher salt and black pepper.
Toss the asparagus to coat evenly and arrange in a single layer on the baking sheet.
Roast in the preheated oven for 10 to 15 minutes, depending on the thickness of the spears, until tender-crisp and lightly browned.
Remove from the oven and serve immediately with fresh lemon wedges.