Preheat your oven to 425°F (220°C) and line a large baking sheet with high-quality parchment paper.
Place the cottage cheese and eggs into a high-speed blender or food processor and blend until the mixture is completely liquid and smooth.
Add the mozzarella cheese, Parmesan cheese, all-purpose flour, baking powder, garlic powder, Italian seasoning, and salt to the blender.
Pulse the blender 5 to 7 times until the dry ingredients are just incorporated into a thick, uniform batter; do not over-mix.
Pour the batter onto the center of the parchment-lined sheet and use an offset spatula to spread it into an even 10-12 inch circle, roughly 1/4 inch thick.
Bake the crust in the center rack for 18 to 20 minutes until the edges are deep golden brown and the surface is firm to the touch.
Remove from the oven, add your preferred pizza sauce and toppings, and return to the oven for an additional 8 to 10 minutes until the cheese is melted and bubbly.
Allow the pizza to rest for 3 to 5 minutes on the baking sheet before slicing to allow the protein structure to fully set.